Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology NASDAQ

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$456.69

$-4.13 (-0.90%)

Open: $458.48 | High: $460.00 | Low: $450.67 | Prev Close: $460.82

Market Cap: $116.00B

Volume: 1.2M | Avg: 1.4M

Last updated: March 09, 2026 at 02:05 AM
Investment Rating
B+

Neutral

Overall Score: 60/100


Rating Breakdown:
DCF Score 4/5
80%
Buy
ROE Score 5/5
100%
Strong Buy
ROA Score 5/5
100%
Strong Buy
D/E Score 2/5
40%
Sell
P/E Score 2/5
40%
Sell
P/B Score 1/5
20%
Strong Sell

Stock Score Analysis
C

Stock Score: 629

Comprehensive Quality Assessment


Component Breakdown:
Efficiency 45
Financial Health 125
Growth 35
Market Sentiment 10
Risk 50
Lower is better
Valuation 9
Momentum 55

Valuation Metrics
Valuation Ratios
P/E Ratio 29.85
P/B Ratio 6.21
P/S Ratio 9.64
EPS $15.30
Beta 0.32
Shares Outstanding 254.00M

Price Range & Moving Averages
52-Week High $519.68
52-Week Low $362.50
SMA 50 $467.45
SMA 200 $437.18

Earnings
Next Earnings May 04, 2026 08:00 PM ET
Financial Ratios
Margins
Gross Margin 86.3%
Operating Margin 35.5%
Net Margin 32.8%

Returns
ROE 22.7%
ROA 15.1%

Liquidity & Leverage
Debt/Equity 0.21
Current Ratio 2.90
Quick Ratio 2.46
Balance Sheet
Total Assets $26.14B
Total Liabilities $7.48B
Total Equity $18.67B

Cash $5.09B
Total Debt $3.88B
Net Debt $-1,205,300,000
Income Statement
Revenue $12.07B
Gross Profit $10.27B
Operating Income $4.76B
Net Income $3.95B

EBITDA $4.97B
Revenue/Share $47.41
Cash Flow
Operating CF $3.63B
CapEx $437.60M
Free Cash Flow $3.19B

Book Value/Share $73.52
Tangible Book/Share $67.56
Equity/Share $73.52
Technical Indicators
RSI (14) 32.36 Neutral
MACD
1.22 Signal: 3.81
Volatility 32.56%
Trading Signal Bearish
Performance & Returns
Total Returns
1 Year +3.64%

Risk-Adjusted Returns
Sharpe Ratio 0.13 Fair
Volatility (Ann.) 34.81% Moderate

vs S&P 500 (SPY)
VRTX (1Y) +3.64%
S&P 500 (1Y) +13.03%
Alpha (Excess Return) -9.4%
Sector Comparison (Healthcare)
Compared to 52 peers in Healthcare
Metric VRTX Sector Avg Percentile
P/E Ratio 29.85 27.61 60%
P/B Ratio 6.21 -19.64 76%
ROE (%) 22.70% -9.72% 74%
Net Margin (%) 32.84% 8.87% 98%
Stock Score 629 542.0 93%
1Y Return (%) +3.64 % +8.23 % 48%
Percentile: 0% = worst in sector, 100% = best in sector
📊 Historical Price Analysis (Last 200 Days)
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Technical Analysis
Ticker Close SMA 5 SMA 8 SMA 13 SMA 50 SMA 200 RSI (14) MACD Volatility (%) Volume Signal SMA Decision
VRTX $456.69 $472.93 $477.14 $476.77 $468.10 $437.34 32.36 1.22 32.56% 224101 Weak Short Price Below SMAs
Candlestick Patterns

There wasn't any recognizable pattern for the VRTX stock

News Sentiment
📊 Ticker 📰 Headline 💭 Sentiment 📡 Source 🔗 URL
VRTX Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It Neutral zacks.com Read More
VRTX Vertex Pharmaceuticals (VRTX) Registers a Bigger Fall Than the Market: Important Facts to Note Negative zacks.com Read More
VRTX Vertex Pharmaceuticals Incorporated (VRTX) Presents at Barclays 28th Annual Global Healthcare Conference Transcript Neutral seekingalpha.com Read More
VRTX Vertex (VRTX) Moves 8.3% Higher: Will This Strength Last? Neutral zacks.com Read More
VRTX Blair William & Co. IL Sells 8,087 Shares of Vertex Pharmaceuticals Incorporated $VRTX Neutral defenseworld.net Read More
Recent Insider Trading

No recent insider trading data available for VRTX

Company Information

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.


CEO Reshma Kewalramani
Employees 6100
Country US
IPO Date 1991-07-24
Exchange NASDAQ
Website https://www.vrtx.com
Sector Healthcare
Industry Biotechnology
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Rating Metrics Explained
DCF Score (Discounted Cash Flow)

Measures the intrinsic value of the stock based on projected future cash flows. A higher score indicates the stock is undervalued relative to its DCF valuation.

ROE Score (Return on Equity)

Evaluates how efficiently a company generates profit from shareholders' equity. Higher ROE indicates better profitability and management effectiveness.

ROA Score (Return on Assets)

Measures how efficiently a company uses its assets to generate profit. A higher ROA means better asset utilization and operational efficiency.

D/E Score (Debt-to-Equity)

Assesses the company's financial leverage and risk. Lower debt-to-equity ratios indicate less financial risk and better balance sheet health.

P/E Score (Price-to-Earnings)

Compares stock price to earnings per share. A lower P/E ratio may indicate the stock is undervalued, while a higher ratio could suggest overvaluation or growth expectations.

P/B Score (Price-to-Book)

Compares market price to book value per share. Lower P/B ratios may indicate undervaluation relative to the company's net asset value.


Rating Recommendations:

Each metric is scored on a scale of 1-5, where the scores are determined by comparing the company's performance against industry benchmarks and historical data:

  • Strong Buy (5/5): Excellent score - strong positive indicator
    • The metric significantly outperforms industry averages (top 20% of companies)
    • Indicates exceptional financial health or attractive valuation in that category
  • Buy (4/5): Good score - positive indicator
    • Above-average performance (top 40% of companies)
    • Shows strong fundamentals with room for improvement
  • Neutral (3/5): Average score - neutral indicator
    • Performance in line with industry median (middle 20%)
    • Neither significantly positive nor negative signal
  • Sell (2/5): Below average - negative indicator
    • Below-average performance (bottom 40% of companies)
    • Suggests weakness in this particular metric
  • Strong Sell (1/5): Poor score - strong negative indicator
    • Significantly underperforms industry (bottom 20%)
    • Indicates potential risk or overvaluation in that category
Note: The overall rating combines all six component scores to provide a comprehensive investment assessment. No single metric should be used in isolation for investment decisions.